A database of hormones and their receptors |
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HMRbase accession number | 10009 |
Swiss-prot Accession number | P09682 (Sequence in FASTA format) |
Description | Glucagon. |
Source organism | Hydrolagus colliei (Spotted ratfish) (Pacific ratfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Holocephali; Chimaeriformes; Chimaeridae; Hydrolagus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the glucagon family. |
Tissue Specificity | Produced by the X-cells of the islets of pancreas |
Post translational modification | N/A |
Function | Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level |
Protein Length | 36 Amino acids |
Molecular weight | 4236 |
References | 1 PubMed abstract 3311036 |
Domain Name | Hormone_2 |
Hormone Name | Glucagon |
Mature Hormone Sequence | HTDGIFSSDYSKYLDNRRTKDFVQWLLSTKRNGANT |
Position of mature hormone in Pre-Hormone protein | 36 Residues from position (1-36) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10486 |
Swiss-prot Accession number | P68076 (Sequence in FASTA format) |
Description | Gonadoliberin-2 (Gonadoliberin II) (Gonadotropin-releasing hormone II)(GnRH-II) (Luteinizing hormone-releasing hormone II) (LH-RH II)(Luliberin II). |
Source organism | Hydrolagus colliei (Spotted ratfish) (Pacific ratfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Holocephali; Chimaeriformes; Chimaeridae; Hydrolagus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 10 Amino acids |
Molecular weight | 1254 |
References | 1 PubMed abstract 1678723 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-2 |
Mature Hormone Sequence | QHWSHGWYPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (1-10) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10493 |
Swiss-prot Accession number | P69058 (Sequence in FASTA format) |
Description | Oxytocin (Ocytocin). |
Source organism | Hydrolagus colliei (Spotted ratfish) (Pacific ratfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Holocephali; Chimaeriformes; Chimaeridae; Hydrolagus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the vasopressin/oxytocin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland |
Protein Length | 9 Amino acids |
Molecular weight | 1010 |
References | 1 PubMed abstract 5366118 |
Domain Name | N/A |
Hormone Name | Oxytocin |
Mature Hormone Sequence | CYIQNCPLG |
Position of mature hormone in Pre-Hormone protein | 9 Residues from position (1-9) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10842 |
Swiss-prot Accession number | P68992 (Sequence in FASTA format) |
Description | Insulin [Contains: Insulin B chain; Insulin A chain]. |
Source organism | Hydrolagus colliei (Spotted ratfish) (Pacific ratfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Holocephali; Chimaeriformes; Chimaeridae; Hydrolagus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver |
Protein Length | 59 Amino acids |
Molecular weight | 6606 |
References | 1 PubMed abstract 3780981 2 PubMed abstract 2646172 |
Domain Name | Insulin |
Hormone Name | Insulin B chain |
Mature Hormone Sequence | VPTQRLCGSHLVDALYFVCGERGFFYSPKPIRELEPLL |
Position of mature hormone in Pre-Hormone protein | 38 Residues from position (1-38) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10843 |
Swiss-prot Accession number | P68992 (Sequence in FASTA format) |
Description | Insulin [Contains: Insulin B chain; Insulin A chain]. |
Source organism | Hydrolagus colliei (Spotted ratfish) (Pacific ratfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Holocephali; Chimaeriformes; Chimaeridae; Hydrolagus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver |
Protein Length | 59 Amino acids |
Molecular weight | 6606 |
References | 1 PubMed abstract 3780981 2 PubMed abstract 2646172 |
Domain Name | Insulin |
Hormone Name | Insulin A chain |
Mature Hormone Sequence | GIVEQCCHNTCSLANLEGYCN |
Position of mature hormone in Pre-Hormone protein | 21 Residues from position (39-59) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |